四氧嘧啶糖尿病大鼠脑内单胺氧化酶活性的变化
Changes in monoamine oxidase activity in rat brain during alloxan diabetes.
作者信息
Mayanil C S, Kazmi S M, Baquer N Z
出版信息
J Neurochem. 1982 Jan;38(1):179-83. doi: 10.1111/j.1471-4159.1982.tb10869.x.
Abstract
The effect of alloxan diabetes on the activity of monoamine oxidase was studied in three regions of the rat brain at various time intervals after the onset of diabetes. It was observed that monoamine oxidase activity was decreased at early time intervals after diabetes, followed by a recovery in all three regions of the brain. A reversal of the effect was observed with insulin administration to the diabetic rats.
摘要
研究了四氧嘧啶糖尿病对糖尿病发病后不同时间间隔大鼠脑三个区域单胺氧化酶活性的影响。观察到糖尿病后早期单胺氧化酶活性降低，随后在脑的所有三个区域恢复。对糖尿病大鼠给予胰岛素后观察到该效应的逆转。
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