Varady S, Friedman E, Yap W T, Lage A, Richie J P
J Urol. 1982 Jul;128(1):171-5. doi: 10.1016/s0022-5347(17)52812-8.
There are no currently accepted synthetic ureteral substitutes. When faced with the need for ureteral replacement, the urologist must resort to pedicle grafts of intestine or bladder. Based on encouraging preliminary work in Europe, we have used a new synthetic vascular substitute, Gore-Tex, to replace segments of ureter in the dog. This material is made of expanded (microporous) polytetrafluoroethylene. In vascular surgery it is currently the preferred material due to its non-wetting and non-clotting surface when used in the arterial and venous beds. Adult mongrel dogs underwent segmental replacement of the right ureter and subtotal replacement of the left ureter with segments of 5-mm. tubed Gore-Tex. All anastomoses were performed with running 6--0 prolene. Antibiotics were given routinely perioperatively. Data on 7 dogs are available. Results indicate that Gore-Tex is well tolerated as a ureteral substitute to bridge gaps between segments of ureter. Anastomoses of Gore-Tex to bladder were not successful, resulting in infection and migration of the prosthesis. Under proper circumstances, Gore-Tex can be a useful potential addition to the urologic armamentarium.
目前尚无被广泛接受的合成输尿管替代物。当面临输尿管替代的需求时，泌尿外科医生必须采用肠管或膀胱带蒂移植物。基于欧洲令人鼓舞的初步研究成果，我们使用了一种新型合成血管替代物——戈尔特斯（Gore-Tex），来替代犬的输尿管节段。这种材料由膨体（微孔）聚四氟乙烯制成。在血管外科手术中，由于其在动静脉血管床中使用时具有不湿润和不凝血的表面，它目前是首选材料。成年杂种犬接受了用5毫米管状戈尔特斯替代右侧输尿管节段和左侧输尿管大部的手术。所有吻合均采用连续6-0聚丙烯缝线进行。围手术期常规给予抗生素。现有7只犬的数据。结果表明，戈尔特斯作为输尿管替代物来连接输尿管节段之间的间隙，耐受性良好。戈尔特斯与膀胱的吻合未成功，导致感染和假体移位。在适当的情况下，戈尔特斯可能会成为泌尿外科器械库中一种有用的补充。
