Doy T G, Hughes D L, Harness E
Res Vet Sci. 1978 Jul;25(1):41-4.
Rats infected three weeks previously with 30 Fasciola hepatica cysts were shown to be highly resistant to oral reinfection, as measured by the recovery of immature flukes from the peritoneal cavity 48 h after challenge and confirmed by liver recoveries three weeks after challenge. Eosinophils were prevalent in the lamina propria of the small intestine three weeks after primary infection and increased markedly after challenge.
结果显示,三周前感染30个肝片吸虫囊蚴的大鼠对口服再感染具有高度抗性,这通过攻击后48小时从腹腔中回收未成熟吸虫来衡量,并在攻击三周后通过肝脏回收得到证实。初次感染三周后,嗜酸性粒细胞在小肠固有层中普遍存在,攻击后显著增加。