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大鼠对肝片吸虫再感染的抵抗力以及肠道嗜酸性粒细胞可能的参与情况。

Resistance of the rat to reinfection with Fasciola hepatica and the possible involvement of intestinal eosinophil leucocytes.

作者信息

Doy T G, Hughes D L, Harness E

出版信息

Res Vet Sci. 1978 Jul;25(1):41-4.

PMID:705047
Abstract

Rats infected three weeks previously with 30 Fasciola hepatica cysts were shown to be highly resistant to oral reinfection, as measured by the recovery of immature flukes from the peritoneal cavity 48 h after challenge and confirmed by liver recoveries three weeks after challenge. Eosinophils were prevalent in the lamina propria of the small intestine three weeks after primary infection and increased markedly after challenge.

摘要

结果显示,三周前感染30个肝片吸虫囊蚴的大鼠对口服再感染具有高度抗性,这通过攻击后48小时从腹腔中回收未成熟吸虫来衡量,并在攻击三周后通过肝脏回收得到证实。初次感染三周后,嗜酸性粒细胞在小肠固有层中普遍存在,攻击后显著增加。

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Res Vet Sci. 1978 Jul;25(1):41-4.
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引用本文的文献

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Evasion of Host Immunity During Fasciola hepatica Infection.肝片形吸虫感染期间对宿主免疫的逃避。
Methods Mol Biol. 2020;2137:107-115. doi: 10.1007/978-1-0716-0475-5_8.
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Fasciola hepatica reinfection potentiates a mixed Th1/Th2/Th17/Treg response and correlates with the clinical phenotypes of anemia.肝片吸虫再感染会增强Th1/Th2/Th17/Treg混合反应,并与贫血的临床表型相关。
PLoS One. 2017 Mar 31;12(3):e0173456. doi: 10.1371/journal.pone.0173456. eCollection 2017.
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Susceptibility of experimental animals to reinfection with Clonorchis sinensis.
实验动物对华支睾吸虫再感染的易感性。
Korean J Parasitol. 2006 Jun;44(2):163-6. doi: 10.3347/kjp.2006.44.2.163.
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Development of resistance to reinfection by Clonorchis sinensis in rats.大鼠对华支睾吸虫再感染的抗性发展
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Cellular reactions in the small intestine of rats after infection with Fasciola hepatica.
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