Zechman F W, Davenport P W
Respir Physiol. 1978 Aug;34(2):267-77. doi: 10.1016/0034-5687(78)90033-6.
Two series of experiments were conducted on 8 healthy subjects to test for temporal differences in the detection of added resistive and elastic loads. In one series of experiments, 5 resistive loads were presented for single inspirations for a total of 10 presentations each. Subjects pressed a signal marker as soon as possible if they detected the load. In the second series, 5 elastic loads were tested using the same protocol The detection time (Tdet) for threshold resistive loads (deltaR50) occurred in mid-inspiration near Vmax whereas the Tdet for threshold D loads (delta E50) occurred near the end of inspiration. The differences in the detection times were significant (P less than 0.001). With suprathreshold loads, detection times progressively decreased reaching a minimum value with total occlusion. These results demonstrate unique temporal differences in the patterns of sensory information generated by added resistive and elastic loads and suggest that the intensity of the information is flow dependent for resistive loads and volume dependent for elastic loads.
对8名健康受试者进行了两组实验，以测试检测附加阻力和弹性负荷时的时间差异。在一组实验中，针对单次吸气呈现5种阻力负荷，每种负荷共呈现10次。如果受试者检测到负荷，应尽快按下信号标记。在第二组实验中，使用相同方案测试了5种弹性负荷。阈值阻力负荷（deltaR50）的检测时间（Tdet）出现在吸气中期接近Vmax处，而阈值弹性负荷（delta E50）的Tdet出现在吸气末期附近。检测时间的差异具有统计学意义（P<0.001）。对于阈上负荷，检测时间逐渐缩短，在完全阻塞时达到最小值。这些结果表明，附加阻力和弹性负荷产生的感觉信息模式存在独特的时间差异，提示阻力负荷的信息强度与流量有关，弹性负荷的信息强度与容积有关。
