甲氧苄啶-磺胺甲恶唑用于疟疾、弓形虫病和头虱病的治疗。

Trimethoprim-sulfamethoxazole in the treatment of malaria, toxoplasmosis, and pediculosis.

作者信息

Hutchinson D B, Farquhar J A

出版信息

Rev Infect Dis. 1982 Mar-Apr;4(2):419-25. doi: 10.1093/clinids/4.2.419.

DOI:10.1093/clinids/4.2.419

Abstract

The status of trimethoprim-sulfamethoxazole (TMP-SMZ) as a chemotherapeutic agent for malaria, toxoplasmosis, and pediculosis is reviewed. The use of TMP-SMZ may be advocated for the treatment of malaria when concurrent bacterial infections are present or when conventional antimalarial agents are not available. Present evidence suggests that TMP-SMZ is effective in the treatment of toxoplasmosis; however, its role in treatment of this disease requires study. Although TMP-SMZ can eliminate head louse infections, topical insecticidal preparations are the preferred treatment.

摘要

本文综述了复方磺胺甲恶唑（TMP-SMZ）作为疟疾、弓形虫病和头虱病化疗药物的现状。当同时存在细菌感染或无法获得传统抗疟药物时，可考虑使用TMP-SMZ治疗疟疾。现有证据表明TMP-SMZ对弓形虫病治疗有效；然而，其在该病治疗中的作用仍需研究。虽然TMP-SMZ可消除头虱感染，但局部用杀虫剂制剂仍是首选治疗方法。