Verghese A, Berk S L, Boelen L J, Smith J K
Arch Intern Med. 1982 Sep;142(9):1642-5.
Group B streptococcal infections, although well studied in neonates, have only recently been appreciated as important infectious agents in adults. Seven cases of Group B streptococcal pneumonia were verified by transtracheal aspiration, blood and sputum cultures, or multiple stab cultures at autopsy. The infections were largely nosocomial and, ultimately, fatal in all seven patients. Our patients were older (average age, 73 years) and much more debilitated than the 13 cases reported in the literature. Diabetes was less common than previously reported. Previous antibiotic therapy was common. Concomitant isolation of another organism (especially Staphylococcus aureus) occurred in five patients. The morphologic findings at autopsy, in one patient, were characterized by a severely necrotizing destructive process. In our experience, Group B streptococcal pneumonia is more common, more devastating, and occurs in an older population than previously reported.
B族链球菌感染,尽管在新生儿中已有充分研究,但直到最近才被视为成人重要的感染病原体。通过经气管抽吸、血液和痰液培养或尸检时的多次穿刺培养,确诊了7例B族链球菌肺炎病例。这些感染大多为医院获得性感染,最终7例患者均死亡。我们的患者年龄较大(平均年龄73岁),比文献报道的13例患者身体更虚弱。糖尿病的发生率低于先前报道。既往使用抗生素治疗很常见。5例患者同时分离出另一种病原体(尤其是金黄色葡萄球菌)。1例患者尸检时的形态学表现为严重的坏死性破坏过程。根据我们的经验,B族链球菌肺炎比先前报道的更常见、更具破坏性,且发生于老年人群。