Sarmiento R, Wilson F M, Khatib R
Department of Medicine, St. John Hospital and Medical Center, Detroit, MI 48236.
Scand J Infect Dis. 1993;25(1):1-6.
A case of group B streptococcal meningitis in an adult is presented with a review of 42 other cases reported in the English literature since 1940. Their median age was 58 years (72.5% were older than 45 years). Male/female ratio was 0.9:1, with male predominance in patients older than 60 years (76.5%). Predisposing illnesses were common but 13.9% of cases reported had no identifiable risk factor. Encephalopathy and bacteremia were frequent (81.3% and 94.4% respectively) and many patients (30%) had other foci of infection. Gram stain of cerebrospinal fluid was positive in 75% of cases. Mortality was 18.4% and 9.7% of survivors had bilateral hearing loss. Thus, this review illustrates that group B streptococcal meningitis in adults is a rare disease which occurs among high risk individuals. It is characterized by frequent encephalopathy, prevalence of other foci of infection and bacteremia with an outcome similar to other types of purulent meningitides.
本文报告了一例成人B族链球菌脑膜炎病例，并回顾了自1940年以来英文文献中报道的其他42例病例。他们的中位年龄为58岁（72.5%的患者年龄超过45岁）。男女比例为0.9:1，60岁以上患者中男性占优势（76.5%）。易感疾病很常见，但报告的病例中有13.9%没有可识别的危险因素。脑病和菌血症很常见（分别为81.3%和94.4%），许多患者（30%）有其他感染灶。75%的病例脑脊液革兰氏染色呈阳性。死亡率为18.4%，9.7%的幸存者有双侧听力丧失。因此，本综述表明成人B族链球菌脑膜炎是一种罕见疾病，发生于高危个体中。其特点是脑病常见、存在其他感染灶和菌血症，其结局与其他类型的化脓性脑膜炎相似。
