亚精胺（多胺）对体外DNA脱嘌呤作用的影响。

The influence of spermidine (polyamines) on DNA depurination in vitro.

作者信息

Andreev O A, Kaboev O K

出版信息

Biochim Biophys Acta. 1982 Jul 30;698(1):100-1. doi: 10.1016/0167-4781(82)90190-7.

Abstract

The influence of the spermidine, spermine and putrescine on the DNA depurination rate was studied. These polyamines protect DNA against depurination. The rate of Col EI DNA depurination at pH 4.3 was decreased over 10-fold by addition of 10 mM polyamines.

摘要

研究了亚精胺、精胺和腐胺对DNA脱嘌呤速率的影响。这些多胺可保护DNA不发生脱嘌呤。在pH 4.3时，添加10 mM多胺可使Col EI DNA的脱嘌呤速率降低10倍以上。