Burgoyne R D, Rose S P
Neurosci Lett. 1980 Oct 2;19(3):343-8. doi: 10.1016/0304-3940(80)90285-2.
The effect of training on a passive avoidance test on incorporation of [3H]fucose into subcellular fractions of the anterior forebrain roof of 1-day-old chicks was determined. Isotope was injected intraperitoneally, and birds tested and killed after 3 h. There was an increase in incorporation in trained compared with untrained control birds in the synaptic membrane (19% elevation, P less than 0.02) and the mitochondrial (14% elevation, P less than 0.05) fractions. Following intracranial injection, increased incorporation in trained birds was seen only in the synaptic membrane fraction (39% elevation, P less than 0.01); this increase in incorporation was not limited to any particular electrophoretically separated glycopeptides, but occurred in all 9 detected peaks.
研究了训练对1日龄雏鸡被动回避试验中[3H]岩藻糖掺入前脑顶部亚细胞组分的影响。同位素经腹腔注射，3小时后对鸟类进行测试并宰杀。与未训练的对照鸟类相比，训练后的鸟类突触膜（升高19%，P<0.02）和线粒体（升高14%，P<0.05）组分中的掺入量增加。颅内注射后，仅在突触膜组分中观察到训练后鸟类的掺入量增加（升高39%，P<0.01）；这种掺入量的增加并不局限于任何特定的经电泳分离的糖肽，而是出现在所有9个检测峰中。
