Ito M, Jastreboff P J, Miyashita Y
Neurosci Lett. 1980 Oct 20;20(1):45-8. doi: 10.1016/0304-3940(80)90231-1.
Retrograde influence of cerebellar cortical lesions upon neurons of the inferior olive was examined in albino rabbits after survival for 2 weeks. Ablation of the flocculus on one side induced a cell loss by 41% accompanied by a size reduction of as much as 27% in the contralateral dorsal cap, the source of climbing fiber afferents to the flocculus. By contrast, after destruction of flocculus Purkinje cells with local injections of 0.1% kainic acid-saline solution, there was no retrograde cell loss in the dorsal cap. However, a slight reduction in cell size (less than 10%) was noted.
在白化兔存活2周后，研究了小脑皮质损伤对下橄榄核神经元的逆行影响。一侧绒球切除导致对侧背帽（即向绒球发出攀缘纤维传入的来源）细胞损失41%，同时细胞大小减少多达27%。相比之下，在局部注射0.1% kainic acid - 生理盐水溶液破坏绒球浦肯野细胞后，背帽中没有逆行性细胞损失。然而，观察到细胞大小略有减小（小于10%）。
