Whitmore W F
Cancer Treat Rep. 1982 Jan;66(1):5-10.
The rationale for further treatment after orchiectomy and the logical basis of the principle therapeutic alternatives in the management of clinical state I nonseminomatous germ cell tumors of the testis have been reviewed. Retroperitoneal lymph node dissection provides the epitome of staging accuracy and a high degree of therapeutic effectiveness in clinical stage I nonseminomatous germ cell tumors of the testis and is associated with minimal early and late morbidity and a low mortality. However, all methods of further active therapy after radical orchiectomy are under legitimate scrutiny in view of the burden of unnecessary therapy, the accuracy of clinical staging, the ability to recognize failures early, and the high probability of successful treatment of such failures.
睾丸切除术后进一步治疗的理论依据以及睾丸临床I期非精原细胞性生殖细胞肿瘤治疗中主要治疗选择原则的逻辑基础已得到综述。腹膜后淋巴结清扫术在睾丸临床I期非精原细胞性生殖细胞肿瘤中体现了分期的准确性和高度的治疗有效性,且早期和晚期发病率极低,死亡率也低。然而,鉴于不必要治疗的负担、临床分期的准确性、早期识别复发的能力以及成功治疗此类复发的高可能性,根治性睾丸切除术后所有进一步积极治疗的方法都受到合理审视。