Thor D H, Wainwright K L, Holloway W R
Dev Psychobiol. 1982 Jan;15(1):1-8. doi: 10.1002/dev.420150102.
Persistence of social attention by male and female laboratory rats was examined following exposure to novel conspecifics. In experiment I we compared performance of castrate female controls. Testosterone significantly prolonged mean social investigation time. Castrate females treated with a 10-day regimen of testosterone propionate to that of intact males and castrate females treated with a relatively high dosage of testosterone failed to differ from intact males. In Experiment II we compared neonatally androgenized female castrates with castrate male and castrate female controls. Postnatal exposure to testosterone increased sensitivity of females to exogenous testosterone in maturity as measured by persistence of social investigation. In Experiment III we compared investigation time of intact and castrate males and females at 10-day intervals from 40 to 80 days of age. Intact males investigated novel conspecifics significantly longer than other groups, with longest investigation times at 60 and 70 days of age. In Experiment IV we compared investigation times of 30-day, 60-day, and 200-day-old males. Sixty-day-old males investigated significantly longer than 30-day-old or 200-day-old groups, which failed to differ from each other. The combined results demonstrate a gender and age-related effect of testosterone on persistence of social investigation.
在让雄性和雌性实验大鼠接触新的同种个体后，对它们的社会注意力持续性进行了研究。在实验I中，我们比较了去势雌性对照的表现。睾酮显著延长了平均社会探究时间。接受丙酸睾酮10天疗程治疗的去势雌性与完整雄性以及接受相对高剂量睾酮治疗的去势雌性相比，与完整雄性没有差异。在实验II中，我们将新生期雄激素化的去势雌性与去势雄性和去势雌性对照进行了比较。通过社会探究的持续性来衡量，出生后接触睾酮增加了雌性在成熟时对外源性睾酮的敏感性。在实验III中，我们比较了40至80日龄的完整和去势雄性及雌性在10天间隔期的探究时间。完整雄性对新同种个体的探究时间明显长于其他组，在60和70日龄时探究时间最长。在实验IV中，我们比较了30日龄、60日龄和200日龄雄性的探究时间。60日龄雄性的探究时间明显长于30日龄或200日龄组，而这两组之间没有差异。综合结果表明，睾酮对社会探究持续性存在与性别和年龄相关的影响。
