Siegel C J, Dockhorn R J
Ann Allergy. 1982 Jan;48(1):9-11.
The differences in children with allergic and nonallergic rhinitis were reviewed. Thirty-two patients were studied prospectively. Ten patients were diagnosed as having allergic rhinitis (AR) on the basis of history correlating with RAST's and elevated IgE for age. Twenty-two patients had no evidence of atopy as a cause for their rhinorrhea and were classified as having vasomotor rhinitis (VMR). In this group 10 patients demonstrated eosinophilic nonallergic rhinitis (ENR). Responsiveness of the various group to medical therapy was noted. It was found that patients with AR and ENR are significantly more responsive to medical therapy than patients with VMR. The authors feel that there is a definite advantage in performing nasal cytology for determining eosinophilia in chronic childhood rhinorrhea.
回顾了过敏性鼻炎和非过敏性鼻炎患儿的差异。前瞻性研究了32例患者。10例患者根据与变应原吸附试验(RAST)相关的病史及年龄特异性IgE升高被诊断为过敏性鼻炎(AR)。22例患者无特应性作为其鼻漏病因的证据,被归类为血管运动性鼻炎(VMR)。在该组中,10例患者表现为嗜酸性粒细胞性非过敏性鼻炎(ENR)。记录了各组对药物治疗的反应性。发现AR和ENR患者对药物治疗的反应明显高于VMR患者。作者认为,在慢性儿童鼻漏中进行鼻细胞学检查以确定嗜酸性粒细胞增多具有明确优势。