Tatum J L, Burke T S, Fratkin M J, Sharpe A R, Goodrich J K
Clin Nucl Med. 1982 Jan;7(1):1-4. doi: 10.1097/00003072-198201000-00001.
Relative spleen/liver activity ratio was determined from posterior projection images using a photodensitometric method. Ratios from scans of 22 patients with proven pancreatic carcinoma (12 from rectilinear scans and 10 from scintillation camera images) were determined and compared to studies from patients documented as normal and to randomly selected liver/spleen imaging studies which had been previously interpreted as normal. The mean ratio from the pancreatic carcinoma group was significantly lower than the means of the respective normal groups (p[t] less than .0001 for rectilinear scans and p[t] less than .001 for scintigrams). There was no significant difference between the means of the proven normal and randomly selected normal groups or between the two pancreatic carcinoma groups. Splenic vascular alteration is discussed as a possible reason for decreased splenic distribution of Tc-99m-sulfur colloid in this patient group.
使用光密度测定法从后位投影图像确定相对脾/肝活性比值。测定了22例经证实的胰腺癌患者扫描的比值（12例来自直线扫描，10例来自闪烁相机图像），并与记录为正常的患者研究以及先前被解释为正常的随机选择的肝/脾成像研究进行比较。胰腺癌组的平均比值显著低于各自正常组的平均值（直线扫描时p[t]<0.0001，闪烁扫描时p[t]<0.001）。经证实的正常组和随机选择的正常组的平均值之间或两个胰腺癌组之间没有显著差异。脾血管改变被讨论为该患者组中Tc-99m-硫胶体脾分布减少的可能原因。
