Waller R M, Fajman W A
Clin Nucl Med. 1982 Jan;7(1):5-7. doi: 10.1097/00003072-198201000-00002.
Metastatic involvement of the spleen is uncommon. Lymphoma is the most common cause of primary and secondary malignant lesions of the spleen, whereas splenic metastases from carcinoma are rare and usually occur in a setting of concomitant carcinomatosis with melanoma, breast, ovary and lung accounting for the principal primary tumors. We report a case of an isolated, focal splenic defect demonstrated by Tc-99m-sulfur colloid scintigraphy which was the only visual evidence of metastatic adenocarcinoma of the colon. To our knowledge this unusual cause of a focal splenic defect on liver-spleen scintigraphy has not been previously described.
脾脏发生转移并不常见。淋巴瘤是脾脏原发性和继发性恶性病变最常见的病因，而癌转移至脾脏则较为罕见，通常发生在伴有癌病的情况下，其中黑色素瘤、乳腺癌、卵巢癌和肺癌是主要的原发肿瘤。我们报告一例经锝-99m-硫胶体闪烁扫描显示的孤立性局灶性脾脏缺损病例，这是结肠转移性腺癌的唯一可见证据。据我们所知，肝脾闪烁扫描中这种导致局灶性脾脏缺损的不寻常病因此前尚未见报道。
