青霉素是四种细菌属的活性位点抑制剂。
Penicillin is an active-site inhibitor for four genera of bacteria.
作者信息
Yocum R R, Amanuma H, O'Brien T A, Waxman D J, Strominger J L
出版信息
J Bacteriol. 1982 Mar;149(3):1150-3. doi: 10.1128/jb.149.3.1150-1153.1982.
Abstract
The hypothesis that penicillin acts as an active-site inhibitor cell wall biosynthesis was tested by a method of partial proteolytic mapping of penicillin-binding sites versus substrate-binding sites in cell wall D-alanine carboxypeptidases. This enzyme was obtained from four genera of bacteria, purified, and tested.
摘要
通过对细胞壁D-丙氨酸羧肽酶中青霉素结合位点与底物结合位点进行部分蛋白水解图谱分析的方法，对青霉素作为活性位点抑制剂抑制细胞壁生物合成这一假说进行了验证。该酶从四个细菌属中获得，经过纯化并进行了测试。
Zotero 插件