Parkin P J, Kendall B E, Marshall J, McDonald W I
J Neurol Neurosurg Psychiatry. 1982 Jan;45(1):1-6. doi: 10.1136/jnnp.45.1.1.
Fifty-one patients with amaurosis fugax were followed for a mean of 4.9 years from their first attack. Females predominated under the age of 50 years in contrast to men who presented in the older age group. Minor permanent visual sequelae occurred in only three patients, but cerebral vascular symptoms were present at some time in just under half the group. A range of abnormalities was identified on cerebral angiography and some of these correlated with certain clinical findings. Twenty patients were treated by surgery and permanent relief of significant improvement in symptoms occurred in 14. A group of patients who were at greater risk of cerebral vascular complications following angiography and surgery was identified. It is concluded that careful patient selection is necessary before surgery is recommended but that in a significant number of cases with relatively focal atheroma confined to one proximal internal carotid artery an excellent long term result following surgery may be expected.
51例一过性黑矇患者自首次发作起平均随访4.9年。50岁以下女性占多数，而男性多在老年组发病。仅3例出现轻微永久性视觉后遗症，但近半数患者曾有过脑血管症状。脑血管造影发现一系列异常，其中一些与特定临床发现相关。20例患者接受了手术治疗，14例症状得到明显改善或永久缓解。确定了一组血管造影和手术后发生脑血管并发症风险较高的患者。得出的结论是，在建议手术前必须仔细选择患者，但在相当数量的病例中，若动脉粥样硬化相对局限于一侧颈内动脉近端，手术有望取得良好的长期效果。
