Wilson L A, Russell R W
Br Med J. 1977 Aug 13;2(6084):435-7. doi: 10.1136/bmj.2.6084.435.
A prospective study of 80 patients presenting with amaurosis fugax was performed in an attempt to relate clinical features to angiographic findings in the internal carotid artery. Carotid bruit, transient cerebral ischaemic attacks, hypertension, and claudication were associated with a high prevalence of angiographic abnormality. Every patient who showed all these features had an operable lesion, as did 88% of those who had three features. In patients over 50 years of age carotid stenosis and atheromatous ulceration were occasionally found in the absence of bruit and transient cerebral ischaemia, but only one patient aged under 50 had an operable lesion and no associated features. Clinical features were therefore valuable in predicting the outcome of angiography, but it seems prudent to restrict angiography to patients aged over 50, who are most likely to benefit from surgery on the carotid artery.
对80例出现一过性黑矇的患者进行了一项前瞻性研究，旨在将临床特征与颈内动脉血管造影结果相关联。颈动脉杂音、短暂性脑缺血发作、高血压和跛行与血管造影异常的高发生率相关。表现出所有这些特征的每一位患者都有可手术治疗的病变，有三项特征的患者中88%也如此。在50岁以上的患者中，偶尔在没有杂音和短暂性脑缺血的情况下发现颈动脉狭窄和动脉粥样硬化溃疡，但50岁以下只有一名患者有可手术治疗的病变且无相关特征。因此，临床特征在预测血管造影结果方面很有价值，但将血管造影限于50岁以上最可能从颈动脉手术中获益的患者似乎是谨慎之举。
