Wolery M, Harris S R
Phys Ther. 1982 Apr;62(4):445-52. doi: 10.1093/ptj/62.4.445.
Although single-subject research design has been discussed at some length in the recent physical therapy and occupational therapy literature, there has been little attempt to describe the procedures used for interpreting the experimental effects of such research. The purpose of this paper is to present the use of two strategies for determining whether changes have occurred as a result of experimental manipulation. The first strategy, visual analysis of graphed data, relies on visual interpretation of changes in data patterns both within and between experimental conditions. The second strategy is the use of statistical procedures such as trend estimation, the Rn statistic, and time series analysis. Finally, the issues of both clinical and statistical significance in interpreting the results of single-subject research are discussed.
尽管单受试者研究设计在近期的物理治疗和职业治疗文献中已有相当篇幅的讨论，但对于描述此类研究实验效应的解释程序却鲜有尝试。本文的目的是介绍两种用于确定是否因实验操纵而发生变化的策略。第一种策略是对图表数据进行视觉分析，它依赖于对实验条件内部和之间数据模式变化的视觉解读。第二种策略是使用统计程序，如趋势估计、Rn统计量和时间序列分析。最后，本文讨论了解读单受试者研究结果时的临床意义和统计学意义问题。
