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胆脂瘤。在长爪沙鼠(Meriones Unguiculaus)中的实验诱导。

Cholesteatoma. Experimental induction in the Mongolian Gerbil, Meriones Unguiculaus.

作者信息

McGinn M D, Chole R A, Henry K R

出版信息

Acta Otolaryngol. 1982 Jan-Feb;93(1-2):61-7. doi: 10.3109/00016488209130853.

DOI:10.3109/00016488209130853
PMID:7064697
Abstract

Surgical ligation of the external auditory canal of the Mongolian gerbil produces aural cholesteatomas that are similar to the spontaneous gerbilline cholesteatoma. Some 6-9 months after ligation of the external auditory canal, these cholesteatomas are in contact with the bone of the middle ear. These induced cholesteatomas were seen to erode bone and displace soft tissue structures, as is typical of human aural cholesteatomas. The induced gerbilline cholesteatoma is an ideal experimental model for the study of the osteolytic characteristics of cholesteatoma.

摘要

对蒙古沙鼠的外耳道进行手术结扎会产生耳胆脂瘤,这些耳胆脂瘤与沙鼠自发产生的胆脂瘤相似。在结扎外耳道约6 - 9个月后,这些胆脂瘤与中耳的骨头接触。这些诱导产生的胆脂瘤会侵蚀骨头并移位软组织结构,这是人类耳胆脂瘤的典型特征。诱导产生的沙鼠胆脂瘤是研究胆脂瘤溶骨特性的理想实验模型。

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