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ABH分泌状态与肺功能

ABH secretor status and pulmonary function.

作者信息

Haines A P, Imeson J D, Meade T W

出版信息

Am J Epidemiol. 1982 Mar;115(3):367-70. doi: 10.1093/oxfordjournals.aje.a113314.

DOI:10.1093/oxfordjournals.aje.a113314
PMID:7064972
Abstract

Among current cigarette smokers in the Northwick Park Heart Study in N.W. London, England, secretors of ABH antigen had a higher mean peak expiratory flow rate than did nonsecretors. The relationship was independent of other factors known to affect peak expiratory flow rate. No significant differences in peak expiratory flow rate by secretor status were detected in nonsmokers or in pipe and cigar smokers, although a smaller difference was seen among secretors and nonsecretors who were ex-cigarette smokers than among those who were current cigarette smokers. It is concluded that secretion of ABH antigen into the respiratory tract may have a protective effect against pulmonary damage by noxious agents.

摘要

在英国伦敦西北部的诺斯威克公园心脏研究中,当前吸烟者中,ABH抗原分泌者的平均呼气峰值流速高于非分泌者。这种关系独立于其他已知影响呼气峰值流速的因素。在不吸烟者、烟斗吸烟者和雪茄吸烟者中,未检测到根据分泌状态划分的呼气峰值流速有显著差异,不过,在既往吸烟者中的分泌者和非分泌者之间观察到的差异,比当前吸烟者中的分泌者和非分泌者之间的差异要小。研究得出结论,ABH抗原分泌到呼吸道中可能对有害因子造成的肺部损伤具有保护作用。

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ABH secretor status and pulmonary function.ABH分泌状态与肺功能
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