Bornschein W
Z Gastroenterol. 1978 Sep;16(9):582-92.
Measurement of the pancreatic exocrine secretion was performed for 20 minutes using a gastrofiberscope. The exocrine pancreas was stimulated by 1 clin. U./kg secretin and 40 ng/kg caerulein as a bolus injection. Aspiration of duodenal juice was performed by a polyaethylen-tube through the biopsy-channel of the endoscope while duodenum distal of the papilla was shut by a baloon-tube, fixed on the distal end of the gastrofiberscope. In 84 patients the investigation was done 87 times. In 11 cases of proved chronic pancreatitis the endoscopic secretin-caerulein-test (SCKT) was pathologic in each case. --Normal values obtained by SCKT were in the range of those obtained by standard secretin-pancreozymin-test with correction of the volume of duodenal juice. Maximal enzyme output was always found in the first five-minute fraction of duodenal juice. Maximal bicarbonate output was found later between 15 and 20 minutes after stimulation. There was a good correlation between maximal enzyme output and maximal bicarbonate output in SCKT on one side and the results of a standard secretin-pancreozymin-test later performed in the same 10 patients. The SCKT is an easy and fast practicable method to be done after routine gastroscopy.
使用纤维胃镜对胰腺外分泌进行20分钟的测量。通过静脉推注1临床单位/千克的促胰液素和40纳克/千克的雨蛙肽刺激胰腺外分泌。通过聚乙烯管经内窥镜活检通道抽吸十二指肠液，同时用固定在纤维胃镜远端的气囊管封闭乳头远端的十二指肠。84例患者共进行了87次检查。在11例确诊为慢性胰腺炎的病例中，内镜促胰液素-雨蛙肽试验（SCKT）均呈病理性。——SCKT获得的正常数值与经十二指肠液量校正后的标准促胰液素-胰酶泌素试验获得的数值范围一致。十二指肠液的最大酶输出量总是出现在最初的5分钟时段内。最大碳酸氢盐输出量出现在刺激后的15至20分钟之间。一方面，SCKT中的最大酶输出量和最大碳酸氢盐输出量与随后在同一10例患者中进行的标准促胰液素-胰酶泌素试验结果之间存在良好的相关性。SCKT是一种在常规胃镜检查后易于快速实施的方法。
