Cavallini G, Mirachian R, Angelini G, Vantini I, Vaona B, Bovo P, Gelpi F, Ederle A, Dobrilla G, Scuro L A
Scand J Gastroenterol. 1978;13(1):3-15. doi: 10.3109/00365527809179800.
Secretin (1 CU/Kg) plus Caerulein (100 ng/Kg) or Cholecystokinin (1 or 2 IvyU/Kg) were given by rapid intravenous injection (Schedule 1) or by continuous infusion (Schedule 2) to 63 control subjects (C) and 69 patients affected by chronic pancreatitis (CP). Duodenal juice was collected for two and four 30-minute periods in schedule 1 and schedule 2, respectively. Volume, bicarbonate, and enzyme content were measured. Secretin-Daerulein, by rapid intravenous injection, showed a strong overlapping between C and CP values and led to some side-effects. Secretin-Caerulein by continuous intravenous infusion gave almost identical results as the Secretin-Cholecystokinin.
向63名对照受试者（C）和69名慢性胰腺炎（CP）患者快速静脉注射（方案1）或持续输注（方案2）促胰液素（1 CU/千克）加雨蛙肽（100纳克/千克）或胆囊收缩素（1或2 IvyU/千克）。在方案1和方案2中，分别在两个和四个30分钟时间段收集十二指肠液。测量体积、碳酸氢盐和酶含量。快速静脉注射促胰液素-雨蛙肽显示对照受试者和慢性胰腺炎患者的值有很大重叠，并导致一些副作用。持续静脉输注促胰液素-雨蛙肽的结果与促胰液素-胆囊收缩素几乎相同。
