Yap P, Pantangco E, Yap A, Yap R
Am J Surg. 1982 Mar;143(3):284-7. doi: 10.1016/0002-9610(82)90091-5.
A retrospective study was made of a consecutive series of 465 patients with histologically proven gastric carcinoma operated on from December 1950 to December 1974. There were 352 men and 113 women, for a male-female ratio of 3.1 to 1. The peak age of incidence was 51 to 55 years. Noncurative surgical procedures were performed in 49.5 percent with no 5 year survivors; 50.5 percent had curative gastric resection. The ulcerating type was the most common lesion, and the pylorus and antrum were the most common primary sites of tumor. Applying the TNM pathologic stage grouping, the study revealed that 3.4 percent of the patients with curative resections were in stage I, 25.5 percent were in stage II and 71 percent in stage III. The 5 year survival rate was 100 percent for stage I, 70 percent for stage II and 20 percent for stage III. Eighty-four patients or 35.7 percent of those with curative gastric resection survived 5 years or longer. The operative mortality was 3.5 percent for the group with noncurative surgical procedures and 2.1 percent for the group with curative gastric resections, giving an overall operative mortality of 2.8 percent for the entire series.
对1950年12月至1974年12月期间连续收治的465例经组织学证实的胃癌患者进行了回顾性研究。其中男性352例，女性113例，男女比例为3.1比1。发病高峰年龄为51至55岁。49.5%的患者接受了非根治性手术，无5年存活者；50.5%的患者接受了根治性胃切除术。溃疡型是最常见的病变类型，幽门和胃窦是最常见的肿瘤原发部位。应用TNM病理分期分组，研究显示，根治性切除患者中3.4%处于I期，25.5%处于II期，71%处于III期。I期的5年生存率为100%，II期为70%，III期为20%。84例患者（占根治性胃切除术患者的35.7%）存活5年或更长时间。非根治性手术组的手术死亡率为3.5%，根治性胃切除术组为2.1%，整个系列的总体手术死亡率为2.8%。
