支气管分泌物中妥布霉素的浓度。

Bronchial secretion concentrations of tobramycin.

作者信息

Alexander M R, Schoell J, Hicklin G, Kasik J E, Coleman D

出版信息

Am Rev Respir Dis. 1982 Feb;125(2):208-9. doi: 10.1164/arrd.1982.125.2.208.

DOI:10.1164/arrd.1982.125.2.208

Abstract

The mean concentrations of tobramycin in bronchial secretions from patients with pneumonia were almost two times greater than secretions from patients free of lung infection. Mean tobramycin bronchial secretion to serum concentration ratios also were higher when obtained from infected lungs (0.66 versus 0.17) These data suggest that lung infection enhances the concentrations of tobramycin in bronchial secretions.

摘要

肺炎患者支气管分泌物中妥布霉素的平均浓度几乎是无肺部感染患者分泌物中浓度的两倍。从感染肺部获取的妥布霉素支气管分泌物与血清浓度的平均比值也更高（分别为0.66和0.17）。这些数据表明，肺部感染会提高支气管分泌物中妥布霉素的浓度。