Berkelman R L, Godley J, Weber J A, Anderson R L, Lerner A M, Petersen N J, Allen J R
Ann Intern Med. 1982 Apr;96(4):456-8. doi: 10.7326/0003-4819-96-4-456.
During a 3-month period, Pseudomonas cepacia was recovered from the peritoneal fluid of 10 patients having chronic dialysis therapy at a peritoneal dialysis center. Six patients developed clinical evidence of peritonitis; one patient developed septicemia. Epidemiologic studies showed that dialysis on specific peritoneal dialysis machines was associated with an increased risk of infection. Laboratory investigation showed contamination of two machines with P. cepacia. Inadequacies in the cleaning and disinfection practices of the automatic peritoneal dialysis machines were identified. Cross-contamination between machines probably occurred through the peritoneal fluid discharge from infected patients during dialysis. Also, the intermittent 2-hour exposure of the machine to 2% formaldehyde may have been inadequate. P. cepacia has not been isolated from the peritoneal fluid of any peritoneal dialysis patient after machine cleaning and disinfection practices were altered.
在3个月的时间里，从一家腹膜透析中心接受慢性透析治疗的10名患者的腹膜液中分离出洋葱伯克霍尔德菌。6名患者出现了腹膜炎的临床证据；1名患者发生了败血症。流行病学研究表明，在特定的腹膜透析机器上进行透析会增加感染风险。实验室调查显示两台机器被洋葱伯克霍尔德菌污染。发现自动腹膜透析机器的清洁和消毒操作存在不足。透析过程中，感染患者的腹膜液排出可能导致机器之间发生交叉污染。此外，机器间歇性暴露于2%甲醛2小时可能并不充分。在改变机器清洁和消毒操作后，未再从任何腹膜透析患者的腹膜液中分离出洋葱伯克霍尔德菌。
