Martone W J, Tablan O C, Jarvis W R
Epidemiology Branch, Center for Infectious Diseases, Atlanta, Georgia 30333.
Eur J Epidemiol. 1987 Sep;3(3):222-32. doi: 10.1007/BF00149728.
Pseudomonas cepacia has occasionally been identified as an epidemic and endemic nosocomial pathogen. In outbreaks, usually one clinical site predominates but many may be involved. Detailed investigations have usually implicated a contaminated liquid reservoir or moist environmental surface as the source. Liquid sources have included a number of different classes of antiseptics and disinfectants such as quaternary ammonium chlorides, biguanides, hexachlorophene, and iodophors. Environmental and patient isolates have had multiply resistant antimicrobial susceptibility patterns. The clinical distinction between colonization and infection may be difficult and may challenge the skills of the clinician. Expenditure of resources needed to solve epidemics is justified in view of the potential virulence of this organism and the high likelihood that an unrecognized but easily eliminated liquid environmental reservoir may be the source.
洋葱伯克霍尔德菌偶尔被确认为一种流行性和地方性医院病原体。在暴发中，通常一个临床部位占主导，但也可能涉及多个部位。详细调查通常表明受污染的液体储存器或潮湿的环境表面是源头。液体来源包括多种不同类别的防腐剂和消毒剂，如季铵氯化物、双胍类、六氯酚和碘伏。环境和患者分离株具有多重耐药的抗菌药敏模式。定植和感染之间的临床区分可能很困难，可能对临床医生的技能构成挑战。鉴于这种病原体的潜在毒力以及未被识别但易于消除的液体环境储存器可能是源头的高可能性，解决疫情所需的资源投入是合理的。
