Clark R A, Rietschel R L
Arch Dermatol. 1982 Mar;118(3):163-5.
The effect of topical steroids on patch test responsiveness was investigated in 15 subjects. A 0.1% triamcinolone acetonide ointment and a control preparation were applied three times daily to opposing sites on the upper part of the inner arms prior to patch testing. From a total of 18 pairs of patch tests applied to the 15 patients, substantial differences in the paired reactions were seen in only three patients after 96 hours. Of these, two had the more intense reaction on the control side, and the third had a greater reaction on the triamcinolone-pretreated side. Previously applied, intermediate-strength topical steroids are unlikely to prevent the detection of contact allergy by patch testing.
对15名受试者研究了局部用类固醇对斑贴试验反应性的影响。在进行斑贴试验前，将0.1%曲安奈德软膏和对照制剂每日3次涂抹于上臂内侧相对的部位。在对这15名患者进行的总共18对斑贴试验中，96小时后仅在3名患者中观察到配对反应有显著差异。其中，2名患者在对照侧的反应更强，第3名患者在曲安奈德预处理侧的反应更大。先前应用的中效局部用类固醇不太可能通过斑贴试验阻止接触性过敏的检测。
