The discovery of bretylium and bethanidine.
作者信息
Green A F
出版信息
Br J Clin Pharmacol. 1982 Jan;13(1):25-34. doi: 10.1111/j.1365-2125.1982.tb01333.x.
Abstract
摘要
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The discovery of bretylium and bethanidine.溴苄铵和苄乙胍的发现。
Br J Clin Pharmacol. 1982 Jan;13(1):25-34. doi: 10.1111/j.1365-2125.1982.tb01333.x.
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Ischemia-induced conduction delay and ventricular arrhythmias: comparative electropharmacology of bethanidine sulfate and bretylium tosylate.缺血诱导的传导延迟和室性心律失常：硫酸苄乙铵和溴苄铵的比较电药理学
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Restoration of tyramine responses by bretylium, BW392C60, bethanidine and monoamine oxidase inhibitors in reserpine-treated rats.在利血平处理的大鼠中，溴苄铵、BW392C60、苄乙胍和单胺氧化酶抑制剂对酪胺反应的恢复作用
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Suppression of ventricular fibrillation and positive inotropic action of bethanidine sulfate, a chemical analog of bretylium tosylate that is well absorbed orally.
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COMPARISON OF THE EFFECTS OF BRETYLIUM, GUANETHIDINE AND BETHANIDINE ON SMOOTH MUSCLE RESPONSES TO DIFFERENT RATES OF SYMPATHETIC NERVE STIMULATION.溴苄铵、胍乙啶和苄胍对平滑肌对不同频率交感神经刺激反应的影响比较
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Bethanidine dose, plasma levels, and antihypertensive effects.苄胍剂量、血浆水平及降压作用。
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Facilitation of ganglionic transmission by some adrenergic neurone blocking drugs.某些肾上腺素能神经元阻断药物对神经节传递的促进作用。
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Systemic hemodynamic effects of bethanidine in essential hypertension.苄乙胍对原发性高血压的全身血流动力学影响。
Circulation. 1975 Jul;52(1):137-40. doi: 10.1161/01.cir.52.1.137.
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Clinical pharmacokinetics of bretylium.
Clin Pharmacokinet. 1985 May-Jun;10(3):248-56. doi: 10.2165/00003088-198510030-00004.
本文引用的文献
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Bethanidine, Guanethidine, and Methyldopa in Treatment of Hypertension: a Within-patient Comparison.苄胍、胍乙啶和甲基多巴治疗高血压：患者自身对照比较
Br Med J. 1968 Jan 20;1(5585):135-44. doi: 10.1136/bmj.1.5585.135.
2
On relationships between structure and nicotine-like stimulant activity in choline esters and ethers.胆碱酯类和醚类化合物中结构与尼古丁样刺激活性之间的关系
Br J Pharmacol Chemother. 1952 Mar;7(1):117-29. doi: 10.1111/j.1476-5381.1952.tb00697.x.
3
Clinical and experimental studies on bretylium tosylate, a new hypotensive agent.新型降压药甲苯磺酸溴苄铵的临床及实验研究
Med J Aust. 1960 Apr 2;47(1):528-32. doi: 10.5694/j.1326-5377.1960.tb76189.x.
4
ADRENERGIC NEURONE BLOCKING AGENTS.肾上腺素能神经元阻断剂
Annu Rev Pharmacol. 1965;5:183-212. doi: 10.1146/annurev.pa.05.040165.001151.
5
INTERACTION OF GUANETHIDINE WITH ADRENERGIC NEURONS.胍乙啶与肾上腺素能神经元的相互作用。
J Pharmacol Exp Ther. 1965 Mar;147:303-12.
6
RESERPINE-INDUCED RELEASE OF DRUGS FROM SYMPATHETIC NERVE ENDINGS.利血平诱导药物从交感神经末梢释放
Life Sci (1962). 1964 Aug;3:839-44. doi: 10.1016/0024-3205(64)90145-6.
7
COMPARISON OF THE EFFECTS OF BRETYLIUM, GUANETHIDINE AND BETHANIDINE ON SMOOTH MUSCLE RESPONSES TO DIFFERENT RATES OF SYMPATHETIC NERVE STIMULATION.溴苄铵、胍乙啶和苄胍对平滑肌对不同频率交感神经刺激反应的影响比较
Br J Pharmacol Chemother. 1964 Apr;22(2):349-55. doi: 10.1111/j.1476-5381.1964.tb02039.x.
8
MONOAMINE OXIDASE INHIBITION BY A SERIES OF COMPOUNDS STRUCTURALLY RELATED TO BRETYLIUM AND GUANETHIDINE.一系列结构与溴苄铵和胍乙啶相关的化合物对单胺氧化酶的抑制作用。
J Pharmacol Exp Ther. 1963 Aug;141:166-72.
9
Actions of bretylium and guanethidine on the uptake and release of [3H]-noradrenaline.溴苄铵和胍乙啶对[3H]-去甲肾上腺素摄取和释放的作用。
Br J Pharmacol Chemother. 1962 Feb;18(1):161-6. doi: 10.1111/j.1476-5381.1962.tb01159.x.
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Evidence for a competitive antagonism of guanethidine by dexamphetamine.右旋苯丙胺对胍乙啶竞争性拮抗作用的证据。
Br J Pharmacol Chemother. 1963 Feb;20(1):17-28. doi: 10.1111/j.1476-5381.1963.tb01293.x.
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