Tverdislov V A, Martseniuk O V, El'-Karadagi S, Perova N V, Gerasimova E N
Biofizika. 1982 Jan-Feb;27(1):164-5.
It is shown that the modifying ability sequence of human plasma lipoproteins from patients with ischemic heart disease (IHD) in respect to BLM made of oxidized cholesterol is [HDL2] less than [LDL] less than [VLDL] less than [HDL3] and differs from that in healthy people which is [VLDL], [LDL] less than [HDL2] less than [HDL3]. It is suggested that changes in lipid-protein compositions of the lipoproteins in the case of IHD determined the alterations of the nonreceptor interactions of the atherogenic and antiatherogenic lipoprotein classes with the cell membranes.
结果表明，缺血性心脏病（IHD）患者的人血浆脂蛋白对由氧化胆固醇制成的博来霉素（BLM）的修饰能力顺序为[HDL2]＜[LDL]＜[VLDL]＜[HDL3]，这与健康人的顺序[VLDL]、[LDL]＜[HDL2]＜[HDL3]不同。有人提出，IHD患者脂蛋白中脂质 - 蛋白质组成的变化决定了致动脉粥样硬化和抗动脉粥样硬化脂蛋白类别与细胞膜非受体相互作用的改变。
