Granberg-Ohman I, Tribukait B, Wijkström H, Alim A, Berlin T
Cancer Genet Cytogenet. 1982 Mar;5(3):227-35. doi: 10.1016/0165-4608(82)90029-2.
A papillary cancer of the bladder [WHO grade 3] was studied with chromosome and DNA analysis. A high frequency of mitoses was noted, and analysis of 151 metaphases revealed a dominating stemline in the pentaploid region. More than 95% of the cells contained double minutes (dm). Flow cytometry showed the dominant stemline to be in the hexaploid region, that is, about 20% above the numerical chromosome value. This difference is generally obtained when these two methods are compared and is not influenced by the presence of dm. Both methods have been complementary in the evaluation of this tumor.
对一例膀胱乳头状癌[世界卫生组织3级]进行了染色体和DNA分析。观察到有丝分裂频率较高，对151个中期细胞的分析显示在五倍体区域有一条主要的干系。超过95%的细胞含有双微体（dm）。流式细胞术显示主要干系位于六倍体区域，即比染色体数值约高20%。比较这两种方法时通常会出现这种差异，且不受双微体存在的影响。这两种方法在该肿瘤的评估中互为补充。
