通过麦角新碱激发试验诊断食管痉挛
Diagnosis of oesophageal spasm by ergometrine provocation.
作者信息
Davies H A, Kaye M D, Rhodes J, Dart A M, Henderson A H
出版信息
Gut. 1982 Feb;23(2):89-97. doi: 10.1136/gut.23.2.89.
Abstract
Oesophageal spasm may mimic the pain of myocardial ischaemia. Forty-two patients who were thought to have angina until investigations failed to show any cardiovascular abnormality, were examined for oesophageal disease. Ergometrine provocation during oesophageal manometry caused significant deterioration in oesophageal motility, associated with familiar pain, in 24 patients. Ten age-matched controls were examined in a similar way and ergometrine produced motility changes in four and pain in two. Six volunteers with coronary artery stenosis and exercise-induced angina did not develop oesophageal motility changes during the pain. Ergometrine provocation is useful in establishing the diagnosis of oesophageal spasm in patients with recurrent angina-like pain but no cardiac abnormality.
摘要
食管痉挛可能会模拟心肌缺血的疼痛。42名患者在检查未发现任何心血管异常之前一直被认为患有心绞痛，随后对他们进行了食管疾病检查。在食管测压过程中，麦角新碱激发试验导致24例患者食管动力显著恶化，并伴有熟悉的疼痛。以类似方式检查了10名年龄匹配的对照者，麦角新碱使4人出现动力变化，2人出现疼痛。6名患有冠状动脉狭窄和运动诱发心绞痛的志愿者在疼痛期间未出现食管动力变化。麦角新碱激发试验有助于诊断反复出现心绞痛样疼痛但无心脏异常的患者是否患有食管痉挛。
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