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睾酮对雏鸡记忆形成的作用期限有限。

Limited period of actin of testosterone on memory formation in the chick.

作者信息

Clifton P G, Andrew R J, Gibbs M E

出版信息

J Comp Physiol Psychol. 1982 Apr;96(2):212-22. doi: 10.1037/h0077883.

DOI:10.1037/h0077883
PMID:7068984
Abstract

Domestic chicks will normally peck readily at small colored beads. However, a peck at a bead with an unpleasant taste usually results in a long-lasting aversion to beads of that type. If prior experience ("pretraining") of a bead of the type that is to be used in a later aversive training trial is given to testosterone-treated chicks, it interferes with the retention of avoidance. Interference by pretraining is effective only within sharply defined periods of time: when the pretraining-training interval is either less than 2 min (short term) or greater than about 25 min (long term). When pretraining and training are separated by 90 min or more, the steroid can be effective when injected up to 30 min after pretraining. It appears to change the character of the consolidating memory trace of pretraining in such a way as to make the consolidating memory trace of pretraining in such a way as to make the consolidation of later, contradictory information from training loss likely. The initial storage of this information is apparently unaffected, since retention does not begin to decay until 30-60 min after training. Sort-term interference leads to loss of avoidance within 5 min of training and can be used to demonstrate that the latency of action of the hormone in this task is less than 20 min following a subcutaneous injection.

摘要

家鸡通常会轻易啄食小的彩色珠子。然而,啄食带有难吃味道的珠子通常会导致对该类型珠子产生长期的厌恶。如果将用于后期厌恶训练试验的那种珠子的先前经验(“预训练”)给予经睾酮处理的小鸡,这会干扰回避行为的保持。预训练的干扰仅在严格限定的时间段内有效:当预训练与训练的间隔时间小于2分钟(短期)或大于约25分钟(长期)时。当预训练和训练间隔90分钟或更长时间时,在预训练后长达30分钟注射类固醇可能有效。它似乎以某种方式改变了预训练巩固记忆痕迹的性质,从而使得来自训练的后期矛盾信息的巩固变得可能失败。此信息的初始存储显然未受影响,因为直到训练后30 - 60分钟保持才开始衰退。短期干扰会导致在训练后5分钟内失去回避行为,并且可用于证明皮下注射后该激素在此任务中的作用潜伏期小于20分钟。

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