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“金发”,草原鹿鼠的一种新突变,影响皮毛、皮肤和眼睛色素沉着。

Blonde, a new mutation in Peromyscus maniculatus affecting fur, skin, and eye pigmentation.

作者信息

Pratt B M, Robbins R J

出版信息

J Hered. 1982 Jan-Feb;73(1):69-70. doi: 10.1093/oxfordjournals.jhered.a109578.

Abstract

An autosomal recessive mutation affecting hair and eye pigmentation was discovered in the F2 progeny of wild-type deer mice, (Peromyscus maniculatus), trapped near East Lansing, Michigan. When homozygous, the mutation (designated as blonde, bl), reduces both black and yellow pigmentation deposited in the fur, reduces or eliminates pigmentation in the non-follicular melanocytes of the outer ear, peri-orbital skin and tail, slightly reduces the amount of pigmentation in the choroidal melanocytes, and completely eliminates pigmentation of the retinal epithelium.

摘要

在密歇根州东兰辛附近捕获的野生型鹿鼠(白足鼠)的F2后代中发现了一种影响毛发和眼睛色素沉着的常染色体隐性突变。纯合时,该突变(命名为金发,bl)会减少沉积在皮毛中的黑色和黄色色素沉着,减少或消除外耳、眶周皮肤和尾巴的非毛囊黑素细胞中的色素沉着,略微减少脉络膜黑素细胞中的色素沉着量,并完全消除视网膜上皮的色素沉着。

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