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三州中毒状态综合征研究。I. 流行病学调查结果。

Tri-state toxic-state syndrome study. I. Epidemiologic findings.

作者信息

Osterholm M T, Davis J P, Gibson R W, Mandel J S, Wintermeyer L A, Helms C M, Forfang J C, Rondeau J, Vergeront J M

出版信息

J Infect Dis. 1982 Apr;145(4):431-40. doi: 10.1093/infdis/145.4.431.

DOI:10.1093/infdis/145.4.431
PMID:7069223
Abstract

Eighty women who had onset of toxic-shock syndrome (TSS) between October 1, 1979, and September 19, 1980, and 160 age- and sex-matched neighborhood controls participated in this study to evaluate risk factors associated with TSS in women. Of the 80 women, 76 had onset of illness during their menstrual periods. The odds ratio for developing menses-associated TSS with any use of tampons compared with no use of tampons was 18.01 (P less than 0.001). The odds ratios ranged from 5.29 to 27.5 for individual brand use compared with no use. When exclusive use of a particular tampon brand was compared with exclusive use of all other brands. Rely (Procter and Gamble, Cincinnati, Ohio) was the only brand with a significantly increased odds ratio (2.49; P = 0.005). By multiple logistic regression analysis, the risk of TSS was more closely associated with tampon fluid capacity (absorbency) than with the use of all tampon brands.

摘要

1979年10月1日至1980年9月19日期间发病的80名中毒性休克综合征(TSS)女性患者,以及160名年龄和性别匹配的社区对照者参与了本研究,以评估女性TSS的相关危险因素。在这80名女性中,76名在月经期间发病。使用任何卫生棉条与不使用卫生棉条相比,发生与月经相关的TSS的比值比为18.01(P<0.001)。与不使用相比,各品牌单独使用时的比值比在5.29至27.5之间。当将特定品牌卫生棉条的独家使用与所有其他品牌的独家使用进行比较时。高洁丝(宝洁公司,俄亥俄州辛辛那提)是唯一比值比显著升高的品牌(2.49;P = 0.005)。通过多因素逻辑回归分析,TSS的风险与卫生棉条的液体容量(吸收性)的关联比与所有卫生棉条品牌的使用更为密切。

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