Bassiouny A, Maher A, Bucci T J, Moawad M K, Hendawy D S
J Laryngol Otol. 1982 Mar;96(3):215-28. doi: 10.1017/s0022215100092458.
Increasing numbers of cases of chronic maxillary sinusitis are encountered which resist frequent sinus irrigation and treatment of predisposing factors. The antral washouts are of unusual consistencies and colours. The antral washouts of six cases were investigated by culture and microscopic examination and proved to contain fungal colonies. Antroscopy was a valuable asset in diagnosis. One patient had a Caldwell-Luc operation and daily irrigation through an indwelling polythene tube followed by daily instillation of clotrimazole (Canesten). The five patients who refused operation were treated by repeated bi-weekly antral washouts followed by instillation of clotrimazole. Weekly samples of antral secretions were examined by culture and microscopic examination until they were free for four consecutive weeks. We believe that frequent antral irrigation and local instillation of a broad-spectrum antimycotic drug--preferably after debridement--is the treatment of choice for antromycosis.
慢性上颌窦炎病例日益增多，这些病例对频繁的鼻窦冲洗及诱发因素的治疗均有抵抗。窦腔冲洗物的质地和颜色异常。对6例患者的窦腔冲洗物进行了培养和显微镜检查，结果证明其中含有真菌菌落。鼻窦镜检查在诊断中是一项宝贵的手段。1例患者接受了柯-陆氏手术，并通过留置的聚乙烯管每日冲洗，随后每日滴注克霉唑（凯妮汀）。5例拒绝手术的患者接受了每两周重复一次的窦腔冲洗，随后滴注克霉唑。每周对窦腔分泌物样本进行培养和显微镜检查，直至连续四周无异常。我们认为，频繁的窦腔冲洗和局部滴注广谱抗真菌药物——最好在清创后——是鼻窦真菌病的首选治疗方法。
