Krivosheev O G, Stolyarov G K
Life Sci. 1982 Mar 1;30(9):779-83. doi: 10.1016/0024-3205(82)90613-0.
A significant number of rats (31-68%) subjected to pain stimulation (intraperitoneal injection of 1% or 5% acetic acid, 5 ml/kg), immobilization stress (6 hrs in a supine position) or cold stress (3 hrs at 4-6 degrees C) exhibited postural asymmetry of hind limbs after spinal cord transection at T7 level. The number of rats with right and left limb flexions was approximately equal. Naloxone (2 mg/kg intraperitoneally) prevented the development of postural asymmetry induced by pain and stress stimuli. Postural asymmetry of hind limbs appears to be due to an asymmetric CNS response to stress and pain stimuli. Our data imply that endogenous opioid peptides and opiate receptors may be involved in the regulation of this response.
相当数量的大鼠（31%-68%）在接受疼痛刺激（腹腔注射1%或5%乙酸，5毫升/千克）、固定应激（仰卧位6小时）或冷应激（4-6摄氏度3小时）后，在T7水平脊髓横断后出现后肢姿势不对称。左右肢屈曲的大鼠数量大致相等。纳洛酮（腹腔注射2毫克/千克）可预防由疼痛和应激刺激引起的姿势不对称的发展。后肢姿势不对称似乎是由于中枢神经系统对应激和疼痛刺激的不对称反应所致。我们的数据表明，内源性阿片肽和阿片受体可能参与了这种反应的调节。
