Chazov E I, Yarigin K N, Trushina E D, Titov M I, Smirnov V N
Experientia. 1981;37(8):887-9. doi: 10.1007/BF01985696.
Enkephalins when applied subarachnoidally induce hind limb postural asymmetry in rats with transected spinal cord. The effect is antagonized by naloxone. Methionine-enkephalin induces predominantly left limb flexions while leucine-enkephalin causes mostly right limb flexions. The data suggest an asymmetry existing in the enkephalinergic system in the rat spinal cord.
脑啡肽蛛网膜下腔给药时,可使脊髓横断大鼠出现后肢姿势不对称。该效应可被纳洛酮拮抗。甲硫氨酸脑啡肽主要诱导左肢屈曲,而亮氨酸脑啡肽主要引起右肢屈曲。这些数据表明大鼠脊髓中脑啡肽能系统存在不对称性。