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鼻部实验手术。I. 气流与杯状细胞密度。

Experimental surgery on the nose. I. Airflow and goblet-cell density.

作者信息

Mogensen C, Tos M

出版信息

Acta Otolaryngol. 1978 Sep-Oct;86(3-4):289-97. doi: 10.3109/00016487809124749.

DOI:10.3109/00016487809124749
PMID:707070
Abstract

In rabbits the nasal vestibule was surgically occluded on one side. The rabbits were observed for varying periods, maximum 90 days. The mucosa of the septum was removed from both sides, stained by the PAS-alcian blue whole-mount method, and the goblet cells were counted. The difference in goblet-cell density between the occluded and open side of the nose was less than expected according to previous reports. A completely abolished air flow for 3 months caused only some increase in density. During the first 16 days there was an increase in density on the occluded as well as on the open side of the nose. This can hardly have been due to altered airflow, but must be attributed to an irritative action by the operation upon the nasal mucosa.

摘要

在兔子身上,一侧鼻腔前庭被手术闭塞。对兔子进行了不同时间段的观察,最长观察90天。从两侧切除鼻中隔黏膜,采用过碘酸雪夫氏(PAS)-阿尔辛蓝整装染色法染色,并对杯状细胞进行计数。与之前的报道相比,闭塞侧和未闭塞侧鼻子的杯状细胞密度差异小于预期。3个月完全无气流仅导致密度略有增加。在最初的16天里,闭塞侧和未闭塞侧鼻子的杯状细胞密度均有所增加。这几乎不可能是由于气流改变所致,而必定归因于手术对鼻黏膜的刺激作用。

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Experimental surgery on the nose. I. Airflow and goblet-cell density.鼻部实验手术。I. 气流与杯状细胞密度。
Acta Otolaryngol. 1978 Sep-Oct;86(3-4):289-97. doi: 10.3109/00016487809124749.
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