Ito S, Matsubara Y, Sihibata A
Tohoku J Exp Med. 1982 Jan;136(1):109-10. doi: 10.1620/tjem.136.109.
In order ot elucidate the releasing mechanism of gut neurotensin, plasma radioimmunoassayable neurotensin (RNT) was measured in dogs after intrajejunal administration of various nutrients. Transient and slight increases of plasma RNT were found after administration of glucose and saturated fatty acid. In contrast, remarkably raised plasma RNT levels were seen after administration of an amino acid mixture and of unsaturated fatty acid. The findings suggested that gut neurotensin may play roles in digestion and absorption of amino acid and some fatty acids.
为了阐明肠道神经降压素的释放机制，在给狗空肠内注射各种营养素后，检测了血浆中可通过放射免疫法测定的神经降压素（RNT）。给予葡萄糖和饱和脂肪酸后，血浆RNT出现短暂轻微升高。相比之下，给予氨基酸混合物和不饱和脂肪酸后，血浆RNT水平显著升高。这些发现表明，肠道神经降压素可能在氨基酸和某些脂肪酸的消化吸收中起作用。
