Priest J B, Oei T O, Moorehead W R
Am J Clin Pathol. 1982 Mar;77(3):285-9. doi: 10.1093/ajcp/77.3.285.
Examination of 19 serum biochemical and hematologic parameters in a group of white male runners, ranging in age from 23 to 47 years, just prior to and immediately after a 13-mile "mini-marathon," demonstrated a significant increase, by paired Student t-test, in mean values of: K+, BUN, creatinine, CK, LDH, AST (SGOT), alkaline phosphatase, bilirubin, uric acid and leukocyte counts. Prevailing environmental conditions were such as to produce no significant hemoconcentration. Using this group's statistics and this hospital laboratory's upper limits of normal, the percentage of values above two SDs are, for the resting state: K+ 7%, BUN 7%, creatinine 0%, CK 21%, LDH 21%, AST 0%, alkaline phosphatase 0%, bilirubin 7%, uric acid 7%, and leukocyte count 0%. Post-exertional values above normal limits are: K+ 7%, BUN 21%, creatinine 21%, CK 93%, LDH 86%, AST 0%, alkaline phosphatase 0%, bilirubin 14%, uric acid 36%, and leukocyte 71%. Consequently, abnormally high values for K+, BUN, creatinine, CK, LDH, bilirubin, uric acid, and leukocyte counts can often be expected in some patients who exercise heavily. The degree of the abnormality will depend on the level and length of exercise as well as the elapsed time between exercise and testing.
对一组年龄在23至47岁之间的白人男性跑步者，在一场13英里“迷你马拉松”比赛之前和之后立即进行了19项血清生化和血液学参数检测。通过配对学生t检验发现，以下各项的平均值显著升高：钾离子（K+）、尿素氮（BUN）、肌酐、肌酸激酶（CK）、乳酸脱氢酶（LDH）、天门冬氨酸氨基转移酶（AST，即谷草转氨酶SGOT）、碱性磷酸酶、胆红素、尿酸和白细胞计数。当时的环境条件并未导致明显的血液浓缩。根据该组数据以及本院实验室的正常上限，处于静息状态时，高于两个标准差的值所占百分比分别为：K+ 7%、BUN 7%、肌酐0%、CK 21%、LDH 21%、AST 0%、碱性磷酸酶0%、胆红素7%、尿酸7%、白细胞计数0%。运动后高于正常范围的值分别为：K+ 7%、BUN 21%、肌酐21%、CK 93%、LDH 86%、AST 0%、碱性磷酸酶0%、胆红素14%、尿酸36%、白细胞71%。因此，在一些剧烈运动的患者中，常常可以预期钾离子、尿素氮、肌酐、肌酸激酶、乳酸脱氢酶、胆红素、尿酸和白细胞计数会出现异常高值。异常程度将取决于运动的强度和时长以及运动与检测之间的时间间隔。
