Diwan A R, Coker-Vann M, Brown P, Subianto D B, Yolken R, Desowitz R, Escobar A, Gibbs C J, Gajdusek D C
Am J Trop Med Hyg. 1982 Mar;31(2):364-9. doi: 10.4269/ajtmh.1982.31.364.
An enzyme-linked immunosorbent assay (ELISA) for the detection of antibody to cysticerci of Taenia solium has been developed that employs a pork muscle antigen control for the cysticercus test antigen, somewhat improving the serological distinction between infected and uninfected subjects. Serum antibody to cysticercus was detected in 79% of classical neurocysticercosis patients from Mexico, and in 61% of a group of cysticercosis patients with an unusually rapid invasion of the central nervous system in an endemic focus of disease in Irian Jaya. Antibody was absent in a group of healthy American laboratory personnel, and in residents of a non-endemic region of Papua New Guinea. Additional test on sera from patients with other parasitic diseases showed that cross-reactivity may occur in some patients with schistosomiasis, echinococcosis, and possibly angiostrongyliasis; however, these parasites are not known to cause human infection in Irian Jaya.
已开发出一种用于检测猪带绦虫囊尾蚴抗体的酶联免疫吸附测定（ELISA），该方法采用猪肉肌肉抗原作为囊尾蚴检测抗原的对照，在一定程度上改善了感染与未感染个体之间的血清学区分。在来自墨西哥的79%的典型神经囊尾蚴病患者以及伊里安查亚一个疾病流行区中一组中枢神经系统遭受异常快速侵袭的囊尾蚴病患者中检测到了囊尾蚴血清抗体。一组健康的美国实验室工作人员以及巴布亚新几内亚一个非流行区的居民体内未检测到抗体。对患有其他寄生虫病患者的血清进行的额外检测表明，血吸虫病、棘球蚴病以及可能的管圆线虫病患者中可能会出现交叉反应；然而，在伊里安查亚，这些寄生虫不会导致人类感染。
