Medicine Department, King Edward Medical University & Mayo Hospital, Lahore, 54000, Pakistan.
J Med Case Rep. 2024 Sep 11;18(1):439. doi: 10.1186/s13256-024-04702-0.
Potassium nitrate poisoning is a rare but potentially serious condition that can result in methemoglobinemia and subsequent cyanosis. This case report presents a unique instance of rapid-onset methemoglobinemia resulting from the ingestion of a traditional medicine preparation containing potassium nitrate, known as "kalmi shora."
A 14-year-old Pakistani boy reported to the emergency department with a history of sudden-onset headache, drowsiness agitation, irritability, and generalized cyanosis. Pulse oximetry showed a concerning oxygen saturation level of 58%, whereas arterial blood gas analysis revealed a normal partial pressure of oxygen (90 mmHg). The profile of abrupt onset of symptoms, generalized cyanosis, and the discrepancy between the partial pressure of oxygen and oxygen saturation readings necessitated a comprehensive assessment including inquiries into potential toxins. The peculiar appearance of the blood, resembling chocolate in color, further indicated the possibility of methemoglobinemia. The patient was successfully treated with methylene blue, leading to a prompt resolution of symptoms.
This case highlights the significance of considering toxin exposures, such as traditional-medicine-induced poisoning, in emergency settings. The report contributes to the medical literature by highlighting the potential risks associated with traditional remedies and emphasizes the critical role of prompt diagnosis and intervention in optimizing patient outcomes. Recognition of the specific etiology of methemoglobinemia, in this case, traditional medicine ingestion, is essential for effective management in emergency medicine.
硝酸钾中毒是一种罕见但潜在严重的病症,可导致高铁血红蛋白血症和随后的发绀。本病例报告介绍了一个独特的高铁血红蛋白血症快速发作的实例,原因是摄入了一种含有硝酸钾的传统药物制剂,称为“kalmi shora”。
一名 14 岁的巴基斯坦男孩因突发头痛、嗜睡、烦躁不安、易怒和全身发绀到急诊就诊。脉搏血氧饱和度仪显示令人担忧的氧饱和度水平为 58%,而动脉血气分析显示正常的氧分压(90mmHg)。症状突然发作、全身发绀以及氧分压和氧饱和度读数之间的差异需要进行全面评估,包括询问潜在毒素的情况。血液呈巧克力色的特殊外观进一步表明存在高铁血红蛋白血症的可能性。患者成功接受亚甲蓝治疗,症状迅速缓解。
本病例强调了在急诊环境中考虑毒素暴露(如传统药物引起的中毒)的重要性。该报告通过强调与传统疗法相关的潜在风险,为医学文献做出了贡献,并强调了在优化患者结局方面,及时诊断和干预的关键作用。在急诊医学中,识别高铁血红蛋白血症的具体病因(在本例中为传统药物摄入)对于有效管理至关重要。