Squire L R
Annu Rev Neurosci. 1982;5:241-73. doi: 10.1146/annurev.ne.05.030182.001325.
In agreement with the neuropsychological findings, available anatomical data from patients with diencephalic or bitemporal amnesia suggest that these amnesias need not result from damage to a single functional system. In the case of diencephalic amnesia, the mammillary bodies and the dorsomedial thalamic nucleus have been implicated, but it is not yet clear which structure deserves the greater emphasis. In the case of bitemporal amnesia, the evidence suggests that the hippocampal formation plays a crucial role in memory functions; the possibility also needs to be considered that the hippocampal formation and amygdala may function conjointly in this regard. An alternative possibility that temporal stem damage is responsible for amnesia now seems quite unlikely.
与神经心理学研究结果一致,来自间脑性或双颞叶失忆症患者的现有解剖学数据表明,这些失忆症不一定是由单一功能系统受损所致。就间脑性失忆症而言,乳头体和丘脑背内侧核被认为与之有关,但尚不清楚哪个结构更应受到重视。就双颞叶失忆症而言,证据表明海马结构在记忆功能中起关键作用;还需要考虑海马结构和杏仁核在这方面可能共同发挥作用的可能性。现在看来,颞叶干损伤导致失忆症这种可能性相当小。