Bernhoft R A, Pellegrini C A, Way L W
Arch Surg. 1982 May;117(5):631-5. doi: 10.1001/archsurg.1982.01380290081014.
We studied the clinical course of 35 patients with refractory ascites who underwent 51 peritoneovenous shunts. Nine of them had hepatorenal syndrome (HRS). Operative complications included shunt malfunction, shunt infection, ascitic leak, fluid overload, and disseminated intravascular coagulation. Two of the patients without HRS died postoperatively. The survival rate in this group was 67% at one year and 43% at two years. Ascites was completely controlled in 83% of the survivors at two months and 50% at two years. Neither survival nor shunt patency were predictable. The shunt reversed HRS in three patients, but failed to do so in the other six. Late complications included shunt malfunction and infection. During the first two years of follow-up, five patients bled from esophageal varices. Liver failure was the sole cause of late death. Peritoneovenous shunt should be reserved for patients with truly refractory ascites, for whom it provides excellent palliation.
我们研究了35例接受51次腹腔静脉分流术的顽固性腹水患者的临床病程。其中9例患有肝肾综合征(HRS)。手术并发症包括分流器故障、分流器感染、腹水渗漏、液体超负荷和弥散性血管内凝血。2例无HRS的患者术后死亡。该组患者1年生存率为67%,2年生存率为43%。83%的幸存者在两个月时腹水得到完全控制,50%的幸存者在两年时腹水得到完全控制。生存率和分流器通畅性均无法预测。分流术使3例患者的HRS得到逆转,但其他6例未成功。晚期并发症包括分流器故障和感染。在随访的前两年中,5例患者发生食管静脉曲张出血。肝衰竭是晚期死亡的唯一原因。腹腔静脉分流术应仅用于真正顽固性腹水的患者,该手术可为其提供良好的姑息治疗。