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LeVeen分流术用于肝硬化顽固性腹水的择期治疗。对140例患者的前瞻性研究。

The LeVeen shunt in the elective treatment of intractable ascites in cirrhosis. A prospective study on 140 patients.

作者信息

Smadja C, Franco D

出版信息

Ann Surg. 1985 Apr;201(4):488-93. doi: 10.1097/00000658-198504000-00014.

Abstract

One hundred and forty patients with an intractable ascites complicating a chronic liver disease received a peritoneovenous shunt (PVS) using the LeVeen valve. Operative mortality was ten per cent but was 25% in patients with severe liver failure. Intraoperative drainage of ascites sharply decreased postoperative complications and mortality. One-year actuarial survival rate was 81.4%, respectively 77.7%, 61.3%, and 24.7% in patients with good liver function and moderate or severe liver failure. Variceal hemorrhage occurred in 11 patients and late infection in another 11 patients. Thirty-eight patients (30.5%) had recurrence of ascites. This was mostly due to an obstruction on the venous side of the shunt. An elective portacaval shunt had to be done in 23 patients for recurrence of ascites or variceal bleeding. Among the 57 patients still alive at time of writing, 51 were free of ascites. These results suggest that PVS is an efficient operation. This procedure may be largely indicated in the selected and small group of cirrhotic patients with true intractable ascites and moderate or no liver insufficiency.

摘要

140例伴有慢性肝病难治性腹水的患者接受了使用LeVeen瓣膜的腹腔静脉分流术(PVS)。手术死亡率为10%,但在严重肝功能衰竭患者中为25%。术中腹水引流显著降低了术后并发症和死亡率。肝功能良好以及中度或重度肝功能衰竭患者的1年精算生存率分别为81.4%、77.7%、61.3%和24.7%。11例患者发生静脉曲张出血,另有11例患者发生晚期感染。38例患者(30.5%)腹水复发。这主要是由于分流静脉侧梗阻。23例患者因腹水复发或静脉曲张出血不得不进行择期门腔分流术。在撰写本文时仍存活的57例患者中,51例无腹水。这些结果表明PVS是一种有效的手术。该手术在选定的一小群真正患有难治性腹水且肝功能中度不全或无肝功能不全的肝硬化患者中可能有很大的应用指征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed26/1250738/0d52abbe2413/annsurg00110-0100-a.jpg

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