Van den Bercken J H, Cools A R
Behav Brain Res. 1982 Apr;4(4):319-27. doi: 10.1016/0166-4328(82)90058-4.
Behavioural effects of the cholinergics carbachol and atropine given by means of telestimulation were studied in small groups of freely moving Java monkeys. The sequential structure of behavior was analyzed by assessing the contribution of the preceding behaviours of the treated monkey and its partners to the subsequent behaviour of the treated monkey, in terms of information-theoretical statistics. Carbachol increased the overall variability of behaviour in the treated monkey, enhanced the dependency between the preceding and subsequent behaviour of the treated monkey, and slightly decreased the dependency between the current behaviour of the treated monkey and the preceding behavior of its partners. Atropine only increased the dependency between the treated monkey's current behaviour and the preceding behaviour of its partners. The morphology of overt behaviour remained unaffected following the chosen treatments. Analysis of changes in the frequencies of behaviours belonging to different motivational categories (maintenance, sex, aggression, submission and affiliation) revealed that, after intracaudate injections, all categories were affected to the same degree; in contrast, amygdala injections only affected the categories 'aggression' and 'submission'. It is concluded that the caudate nucleus establishes the relative priority of intra-individual and inter-individual constraints on the programming of behaviour, thereby providing flexibility in the execution of ongoing behaviour; the caudate nucleus is not primarily involved in motor control, nor in the control of particular categories of behaviour.
通过远程刺激给予胆碱能药物卡巴胆碱和阿托品后，对自由活动的爪哇猴小群体的行为效应进行了研究。根据信息理论统计，通过评估受试猴子及其同伴先前行为对受试猴子后续行为的贡献，分析了行为的顺序结构。卡巴胆碱增加了受试猴子行为的总体变异性，增强了受试猴子先前行为与后续行为之间的依赖性，并略微降低了受试猴子当前行为与其同伴先前行为之间的依赖性。阿托品仅增加了受试猴子当前行为与其同伴先前行为之间的依赖性。所选治疗后，明显行为的形态未受影响。对属于不同动机类别的行为（维持、性、攻击、顺从和亲和）频率变化的分析表明，尾状核内注射后，所有类别受到的影响程度相同；相比之下，杏仁核注射仅影响“攻击”和“顺从”类别。得出的结论是，尾状核确定了个体内和个体间对行为编程的限制的相对优先级，从而在执行正在进行的行为时提供灵活性；尾状核主要不参与运动控制，也不参与特定行为类别的控制。
