Gussoni M, Veicsteinas A, Sloan A W
Boll Soc Ital Biol Sper. 1982 Mar 15;58(5):191-8.
The kinetics of oxygen uptake (VO2), cardiac output (Q), and heart rate (HR) were studied in three healthy male subjects during onset of exercises up to 750 kpm/min. VO2 was measured on a single breath basis, Q by CO2-N2 rebreathing method at 30" intervals from time 0 to 6 min of exercise, and HR beat by beat. In the transition from rest to exercise, the increase of Q and VO2 follows a single exponential function, while h. r. a double exponential. Average half times of Q and VO2 during the onset of exercise are about 18" and 26" respectively. Q changes seem to anticipate VO2 changes at the first 15-45 s of exercise, while thereafter a proportional increase is observed. This non-linear increase of Q to VO2 at the beginning of exercise may presumably be due to a neurogenic control of h.r. and hence of Q from receptors at muscular level.
在三名健康男性受试者进行高达750千帕米/分钟的运动开始阶段，研究了摄氧量（VO2）、心输出量（Q）和心率（HR）的动力学。VO2通过单次呼吸测量，Q通过二氧化碳 - 氮气再呼吸法在运动开始后0至6分钟每隔30秒测量一次，HR逐搏测量。从静息状态过渡到运动状态时，Q和VO2的增加遵循单指数函数，而心率遵循双指数函数。运动开始阶段Q和VO2的平均半衰期分别约为18秒和26秒。在运动的最初15 - 45秒，Q的变化似乎先于VO2的变化，而此后观察到二者成比例增加。运动开始时Q相对于VO2的这种非线性增加可能是由于神经源性对心率的控制，进而对肌肉水平受体处的心输出量的控制。
