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夸休可尔症:毛发干的电子组织化学研究

Kwashiorkor: an electron histochemical study of the hair shaft.

作者信息

Gummer C L, Dawber R P, Harman R R, King I S

出版信息

Br J Dermatol. 1982 Apr;106(4):407-10. doi: 10.1111/j.1365-2133.1982.tb04532.x.

Abstract

Previous studies on hair in kwashiorkor have been equivocal regarding the normal or abnormal incorporation of amino acids into the hair shaft. In this study we have applied a sensitive electron histochemical technique to transverse sections of scalp hair from children with severe kwashiorkor in order to study its ultrastructure and the incorporation of sulphur-containing amino acids (cystine). We have found no evidence to support the idea that a protein deficient diet in the weaning or post-weaning period directly affects the distribution and relative amounts of sulphur-containing amino acids in the hair shaft in this disease.

摘要

以往关于夸休可尔症患者头发的研究,在氨基酸是否正常掺入毛干这一问题上存在分歧。在本研究中,我们应用了一种灵敏的电子组织化学技术,对患有严重夸休可尔症儿童的头皮毛发横切面进行研究,以探讨其超微结构以及含硫氨基酸(胱氨酸)的掺入情况。我们没有找到证据支持以下观点:断奶期或断奶后期蛋白质缺乏的饮食会直接影响该病患者毛干中含硫氨基酸的分布和相对含量。

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