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酒石黄:加拿大药品中一种潜在有害的染料。

Tartrazine: a potentially hazardous dye in Canadian drugs.

作者信息

MacCara M E

出版信息

Can Med Assoc J. 1982 Apr 15;126(8):910-4.

Abstract

The literature was reviewed to determine the incidence of idiosyncratic reactions to tartrazine. From 4% to 14% of individuals with asthma or allergies or both and from 7% to 20% of persons who are sensitive to acetylsalicylic acid may react to this dye. The mechanism of such reactions is unknown. Pharmaceutical manufacturers and distributors were surveyed and a list was prepared of approximately 450 Canadian pharmaceuticals that contain tartrazine. The 53 pharmaceutical and manufacturers and distributors whose drug products do not contain this dye were also listed. It is recommended that information concerning the tartrazine content of drugs be included on package labels.

摘要

回顾文献以确定对酒石黄特异反应的发生率。4%至14%的哮喘或过敏患者或两者兼具者,以及7%至20%对乙酰水杨酸敏感的人可能会对这种染料产生反应。此类反应的机制尚不清楚。对药品制造商和经销商进行了调查,并列出了约450种含酒石黄的加拿大药品清单。还列出了其药品不含这种染料的53家制药公司、制造商和经销商。建议在包装标签上注明药品的酒石黄含量信息。

本文引用的文献

5
Concerning the nature of intolerance to aspirin.关于对阿司匹林不耐受的性质。
J Allergy. 1967 Nov;40(5):281-93. doi: 10.1016/0021-8707(67)90076-7.
9
Aspirin intolerance. III. Subtypes, familial occurence, and cross-reactivity with tartarazine.
J Allergy Clin Immunol. 1975 Sep;56(3):215-21. doi: 10.1016/0091-6749(75)90092-5.
10
Drugs containing tartrazine dye.含有酒石黄染料的药物。
J Allergy Clin Immunol. 1976 Oct;58(4):456-70. doi: 10.1016/0091-6749(76)90189-5.

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